This is the raw data supporting the findings (both main text and supplementary) for our manuscript "Staphylococcus aureus cell wall structure and dynamics during host-pathogen interaction". Each excel file contains the raw data for each figure. Murine work was carried out according to UK law in the Animals (Scientific Procedures) Act 1986, under Project License P3BFD6DB9 (Staphylococcus aureus and other pathogens, pathogenesis to therapy, University of Sheffield Review Board).